CAF08 Adjuvant Enables Single Dose Protection against Respiratory Syncytial Virus Infection in Murine Newborns

Investigators showed application of cationic adjuvant formulation CAF08, a liposomal vaccine formulation tailored to induce Th 1 immunity in early life via synergistic engagement of Toll-like Receptor 7/8 and the C-type lectin receptor Mincle.