Downregulation of Stem-Loop Binding Protein by Nicotine via α7-Nicotinic Acetylcholine Receptor and Its Role in Nicotine-Induced Cell Transformation

Scientists reported that exposure to liquid nicotine or nicotine aerosol generated from e-cigarette induced downregulation of stem-loop binding protein and polyadenylation of canonical histone mRNAs in human bronchial epithelial cells and in mice lungs.