Engineered Extracellular Vesicles with High Collagen-Binding Affinity Present Superior In Situ Retention and Therapeutic Efficacy in Tissue Repair

Scientists developed a new generation of collagen-binding extracellular vesicles (EVs) which were designed to bind to collagen in the extracellular matrix (ECM) and form an EV-ECM complex to improve EVs’ in situ retention and therapeutic efficacy after transplantation.