NewslettersNeural Cell NewsAPOE4 Drives Inflammation in Human Astrocytes via TAGLN3 Repression and NF-κB ActivationBy lbeveridge - August 17, 20220140Researchers uncovered that APOE4 specifically downregulated TAGLN3, involving histone deacetylases activity, which results in low-grade chronic inflammation and hyperactivated inflammatory responses.[Cell Reports]Full Article