NewslettersHematopoiesis NewsHbS Promotes TLR4-Mediated Monocyte Activation and Pro-inflammatory Cytokine Production in Sickle Cell DiseaseBy Danielle Corrigan - August 23, 20220126Using purified human hemoglobin (Hb), the authors demonstrated that cell-free HbS, unlike HbA or heme, was responsible for a major enhancement in the expression of pro-inflammatory cytokines by human monocytes.[Blood]Abstract