Macrophage Polarization in Placenta Accreta and Macrophage-Trophoblast Interactions

In an in vitro co-culture model, scientists investigated the effects of HTR-8/SVneo trophoblasts cell line on macrophage human monocyte cell line polarization and granulocyte colony-stimulating factor secretion, and also analyzed the effects of THP-1 cells, especially M2-like subtype, on primary trophoblasts and HTR-8 proliferation, invasion, and adhesion.