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SLC45A2 Drives Prostate Cancer Progression through Tumor Promotion and Immune Suppression

[Scientific Reports] Functional experiments showed that SLC45A2 knockdown inhibited the proliferation and migration of LNCaP and DU145 cells, while SLC45A2 overexpression reversed these effects.

Macrophage MR1 Antigen Presentation Promotes MAIT Cell Immunity and Lung Microbiota Modulation

[Science] Depletion of MHC class I-related protein 1 (MR1) in macrophages, dendritic cells, and monocytes changed the composition of the microbiota and impaired mucosal associated invariant T (MAIT) cell responses against bacterial infection.

Elastic Thermoplastic Polyurethane/Graphene Microneedle-Mesh Interfaces via Microfluidic Patterning for Electrophysiology in Neural Organoids

Scientists presented a stretchable mesh electrode array integrated with elastic graphene microneedles for interfacing with human neural organoids and their assemblies. [ACS Nano ] AbstractGraphical Abstract

And-1 Coordinates with Polymerase δ to Regulate Nucleotide Excision Repair and UVB-Induced Skin Tumorigenesis

[Nature Communications] The authors identified a critical role of And-1 in the nucleotide excision repair pathway. Specifically, And-1 accumulates at UV lesion sites in cells upon exposure to UVB. Inhibition of And-1 in human cells compromises the repair of photoproducts in DNA and reduces cell viability following UVB exposure

Deciphering the Crucial Role of IGF2BP3 in Modulating Stemness Traits of Salivary Adenoid Cystic Carcinoma

[Medical Oncology] Leveraging single-cell sequencing data, investigators corroborated the association between insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) and stemness traits within salivary adenoid cystic carcinoma cells.

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