Activation of Pancreatic Stellate Cells Attenuates Intracellular Ca²⁺ Signals Due to Downregulation of TRPA1 and Protects against Cell Death Induced by Alcohol Metabolites

The authors investigated real-time Ca2+ signaling, changes in mitochondrial potential and cell death induced by ethanol metabolites in quiescent vs TGF-β-activated pancreatic stellate cells.