NewslettersMammary Cell NewsProstate Cell NewsThe Drug Efflux Pump MDR1 Promotes Intrinsic and Acquired Resistance to PROTACs in Cancer CellsBy lbeveridge - September 1, 20220156Using proteomic analysis, researchers found intrinsic and acquired resistance mechanisms to proteolysis-targeting chimeras (PROTACs) in cancer cell lines mediated by greater abundance or production of the drug efflux pump MDR1.[Science Signaling]Full Article