MAP7D2 Reduces CD8+ Cytotoxic T Lymphocyte Infiltration through MYH9-HMGB1 Axis in Colorectal Cancer

Through next generation sequencing, scientists identified microtubule-associated protein 7 domain 2 (MAP7D2) as an exploitable therapeutic maneuver to improve the efficacy of immune checkpoint inhibitors for microsatellite stable colorectal cancer therapy.