Transmissible Gastroenteritis Virus Infection Promotes the Self-Renewal of Porcine Intestinal Stem Cells via Wnt/β-Catenin Pathway

The authors showed that transmissible gastroenteritis virus infection initiated interferon and inflammatory responses following the loss of absorptive enterocytes and goblet cells, but did not disturb epithelial integrity but induced the proliferation of intestinal stem cells.