Functions of Exogenous FGF Signals in Regulation of Fibroblast to Myofibroblast Differentiation and Extracellular Matrix Protein Expression

The authors summarize the effects of fibroblast growth factors (FGFs) in fibroblast to myofibroblast differentiation and ECM protein expression and discuss the underlying potential regulatory mechanisms to provide a basis for the clinical application of recombinant FGF protein drugs in treatment of tissue damage.