Delivering Multifunctional Peptide-Conjugated Gene Carrier/miRNA-218 Complexes from Monodisperse Microspheres for Bone Regeneration

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miR-218 was used as an osteogenic miRNA regulator, and a multifunctional peptide-conjugated gene carrier was developed to condense with miR-218 to form PPP-RGI/miR-218 complexes that were further encapsulated into monodisperse injectable microspheres for enhanced bone regeneration.
[ACS Applied Materials & interfaces]
AbstractGraphical Abstract