Dominant-Negative Transforming Growth Factor-β Receptor-Armoured Mesothelin-Targeted Chimeric Antigen Receptor T Cells Slow Tumour Growth in a Mouse Model of Ovarian Cancer

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The in vivo antitumour activity of mesothelin CAR T cells was verified using a patient-derived xenograft mouse model with human tumour-derived cells.
[Cancer Immunology, Immunotherapy]
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