Lipopolysaccharide Induces Placental Mitochondrial Dysfunction in Murine and Human Systems by Reducing MNRR1 Levels via a TLR4-Independent Pathway

In a lipopolysaccharide-induced model of systemic placental inflammation, scientists showed that mitochondrial nuclear retrograde regulator 1 (MNRR1) levels were reduced both in mouse placental tissues in vivo and in human trophoblastic cell lines in vitro.