Exosomal Thioredoxin-1 from Hypoxic Human Umbilical Cord Mesenchymal Stem Cells Inhibits Ferroptosis in Doxorubicin-Induced Cardiotoxicity via mTORC1 Signaling

The authors dcompared the therapeutic effects between normoxic human umbilical cord (Huc) MSCs-derived exosomes (Exo) and hypoxic HucMSCs-Exo on doxorubicin-induced ferroptosis and explored the underlying mechanisms.