Transplanting Neurofibromatosis-1 Gene Knockout Neural Stem Cells Improve Functional Recovery in Rats with Spinal Cord Injury by Enhancing the mTORC2 Pathway

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Lentiviral vectors were used to knock out NF-1, Ricotr (the core member of mTORC2) or NF-1+Ricotr in neural stem cells in vitro and then were were transplanted at the lesion site in a rat model of spinal cord injury.
[Experimental & Molecular Medicine]
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