A20 Interacts with mTORC2 to Inhibit the mTORC2/Akt/Rac1 Signaling Axis in Hepatocellular Carcinoma Cells

Scientists analyzed the relationship between A20 and Rac1 activation, as well as the activity of Akt and mTORC2, two signaling components upstream of Rac1, using gain and loss of function experiments.