Newsletters

[Austrian Academy of Siences] The European Research Council (ERC) has awarded its most prestigious grants to Christoph Bock, Irene Forstner-Müller, and Jürgen Knoblich - a triple success for the Austrian Academy of Sciences (OeAW).

[Nature Microbiology] Investigators developed a human cerebral organoid model to investigate the host and viral determinants of Ebola virus central nervous system persistence.

[Developmental Cell] Scientists reported a multilevel branching lung organoid model generated from primary tip epithelial cells using a robust, chemically defined protocol.

[BMC Medicine] The authors established a standardized allogeneic 3D co-culture platform integrating patient-derived peritoneal metastatic gastric cancer organoids with pooled peripheral blood mononuclear cells from healthy donors.

[ACS Applied Materials & Interfaces] Researchers develop a tumor microenvironment-responsive nanoplatform that selectively disrupts colorectal cancer organoids through synergistic membrane damage, targeted drug release, and reactive oxygen species-mediated cell death.

[Cell Reports Methods] Investigators reported a multilevel branching lung organoid model generated from primary tip epithelial cells using a robust, chemically defined protocol.

[Cell Reports Methods] Scientists show that a simple 3D-printed stirred bioreactor improves retinal organoid yield and quality by maintaining physiological oxygen levels during differentiation.

[iScience] The authors develop patient-derived oral cancer organoids that accurately predict chemotherapy response and identify molecular drivers of drug resistance, supporting personalized treatment strategies.

[Trends in Biotechnology] Scientists highlight advances in 3D microelectrode array technology, enabling real-time, label-free monitoring of organoids and microphysiological systems for disease modeling and drug discovery.

[Journal of Translational Medicine] The authors summarize recent advances in pancreatic organoid and organoid-on-a-chip technologies, focusing on their applications in pancreatic disease modeling, therapeutic screening, and potential relevance to personalized treatment.

[University of North Carolina at Chapel Hil] Dr. Melissa Troester received a Leadership Grant from Susan G. Komen as part of a continuing commitment to accelerating breast cancer research. The new grant will support Troester’s advances in spatial biology – an understanding of how distances between cancer cells and immune cells alter breast cancer outcomes.

[Stem Cell Reviews and Reports] Researchers outline an integrative framework connecting ferroptosis, epithelial-mesenchymal transition plasticity, tunneling nanotube-mediated communication and CSC dynamics, offering insights into novel strategies to overcome therapeutic resistance, prevent metastatic dissemination and limit tumor relapse.