Catalpol Inhibits Hepatic Stellate Cell Activation by Reducing the Formation and Changing the Contents of Hepatocyte-Derived Extracellular Vesicles

Mouse serum extracellular vesicles were isolated and identified using nanoparticle tracking analysis and transmission electron microscopy. Mouse hepatocytes (AML12) and primary HSCs were used to investigate the cell-to-cell crosstalk.