Deoxyarbutin Attenuates Severe Acute Pancreatitis via the HtrA2/PGC-1α Pathway

This in vitro study showed that Deoxyarbutin (dA) significantly reduced the necrosis of primary acinar cells and reactive oxygen species accumulation, recovered mitochondrial membrane potential, and ATP exhaustion, while UCF-101 and SR-18292 eliminated the protective effect of dA.