NewslettersCell Therapy NewsCD28-CAR-T Cell Activation through FYN Kinase Signaling Rather Than LCK Enhances Therapeutic PerformanceBy Bob - January 30, 20230150The authors showed that CAR signaling occured in the absence of LCK. This LCK-independent signaling required the related SRC family kinase FYN and a CD28 intracellular domain within the CAR.[Cell Reports Medicine]Full ArticleGraphical Abstract