Histone H2A Deubiquitinases in the Transcriptional Programs of Development and Hematopoiesis: A Consolidated Analysis

Researchers address H2A-DUB functions in epigenetic regulation of mammalian development and tissue maintenance by conducting a meta-analysis of 248 genomics datasets from 32 independent studies, focusing on the mouse model and covering ESCs, hematopoietic, and immune cell lineages.