Acquired Radioresistance in EMT6 Mouse Mammary Carcinoma Cell Line Is Mediated by CTLA-4 and PD-1 through JAK/STAT/PI3K Pathway

The underlying mechanism leading to the development of acquired radioresistance in the EMT6 mouse mammary carcinoma cell line and the potential pathway involved was investigated by comparing differential gene expressions between parental and acquired radioresistance cells.