PDK1-Stabilized LncRNA SPRY4-IT1 Promotes Breast Cancer Progression via Activating NF-κB Signaling Pathway

Researchers found that lncRNA sprouty4-intron transcript 1 (SPRY4-IT1) was regulated by pyruvate dehydrogenase kinase 1 (PDK1) with correlation analysis, and PDK1 upregulated SPRY4-IT1 remarkably in breast cancer cells.