Novel Roles for HMGA2 Isoforms in Regulating Oxidative Stress and Sensitizing to RSL3-Induced Ferroptosis in Prostate Cancer Cells

Scientists analyzed the expression of wild-type vs. truncated high mobility group A2 (HMGA2) and showed that prostate cancer patient tissue and some cell lines expressed increasing amounts of both wild-type and truncated HMGA2 with increasing tumor grade.