PRR15 Deficiency Facilitates Malignant Progression by Mediating PI3K/Akt Signaling and Predicts Clinical Prognosis in Triple-Negative Rather Than Non-Triple-Negative Breast Cancer

Scientists investigated the biological role and clinical applications of proline rich 15 (PRR15) on TNBC. PRR15 gene was differentially expressed between TNBC and non-TNBC patients, previously described as an oncogenic factor in breast cancer.