Inhibition of ACAA1 Restrains Proliferation and Potentiates the Response to CDK4/6 Inhibitors in Triple-Negative Breast Cancer

Researchers identified that acetyl-CoA acyltransferase 1 (ACAA1) was highly expressed in the luminal androgen receptor (LAR) subtype of TNBC compared with adjacent normal tissues in their TNBC proteomics dataset.