RNF125 Attenuates Hepatocellular Carcinoma Progression by Downregulating SRSF1-ERK Pathway

Researchers determined whether the E3 ubiquitin ligase Ring Finger Protein 125 (RNF125) played a role in the proliferation and metastasis of HCC. RNF125 expression in human HCC samples and cell lines was investigated using TCGA dataset mining, qRT‒PCR, western blot, and immunohistochemistry assays.