TRIM37 Exacerbates Hepatic Ischemia/Reperfusion Injury by Facilitating IKKγ Translocation

Researchers identified a potential strategy and provide a fundamental experimental basis for treating hepatic ischemia/reperfusion (I/R) injury. They found that tripartite motif containing 37 (TRIM37) aggravated hepatic I/R injury through the reinforcement of IKK-induced inflammation following dual patterns.