N¹-Methyladenosine Modification of mRNA Regulates Neuronal Gene Expression and Oxygen Glucose Deprivation/Reoxygenation Induction

Researchers first constructed a mouse cortical neuron oxygen glucose deprivation/reoxygenation (OGD/R) model and then used methylated RNA immunoprecipitation and sequencing technology to demonstrate that m1A modification is abundant in neuron mRNAs and dynamically regulated during OGD/R induction.