BLM Helicase Overexpressed in Human Gliomas Contributes to Diverse Responses of Human Glioma Cells to Chemotherapy

Scientists performed comprehensive analyses of BLM expression and functions in glioblastmas and demonstrated high levels of the BLM mRNA and protein in malignant tumors and glioma cell lines, along with abnormal cytoplasmic accumulation of BLM in GBMs.