Combination of STAT3 Inhibitor with Herceptin Reduced Immune Checkpoints Expression and Provoked Anti-Breast Cancer Immunity: An In Vitro Study

Investigators treated SK-BR-3 cells with Herceptin and the signal transducer and activator of transcription 3 (STAT3)-inhibitor, FLLL32, and assessed the apoptosis and expression of apoptosis-related proteins, VEGF, Her-2, and apoptosis targets of STAT3.