AGER1 Deficiency-Triggered Ferroptosis Drives Fibrosis Progression in Nonalcoholic Steatohepatitis with Type 2 Diabetes Mellitus

Researchers observed the histopathological features of the progression of NASH to liver fibrosis as well as hepatocyte epithelial-mesenchymal transition in a mouse model of NASH with type 2 diabetes mellitus, and high-glucose-cultured steatotic human normal liver cells.