Human Umbilical Cord Mesenchymal Stem Cells Derived Exosome Shuttling Mir-129-5p Attenuates Inflammatory Bowel Disease by Inhibiting Ferroptosis

Researchers used small RNA sequencing to find that miR-129-5p was highly expressed in human umbilical cord MSC-derived exosomes, and by predicting its targeting to ACSL4, verified the effect of miR-129-5p on mice inflammatory bowel disease in vivo and human colonic epithelial cells in vitro.