Inhibition of USP7 Induces p53-Independent Tumor Growth Suppression in Triple-Negative Breast Cancers by Destabilizing FOXM1

Investigators found that the oncoprotein Forkhead Box M1 (FOXM1) acted as a potential driver for tumor growth in TNBC and through a proteomic screen, they identified USP7 as a major regulator of FOXM1 in TNBC cells.