NewslettersCell Therapy Newsc-Kit Signaling Potentiates CAR T Cell Efficacy in Solid Tumors by CD28- and IL-2-Independent Co-StimulationBy Bob - June 19, 20230247Researchers used a well-studied mutant c-KIT protein as a co-stimulatory domain to generate CAR T cells with strong IFNγ signaling that were able to overcome the immunosuppressive microenvironment of solid tumors.[Nature Cancer]AbstractPress Release