GABAergic Neurons Differentiated from BDNF- and Dlx2-Modified Neural Stem Cells Restore Disrupted Neural Circuits in Brainstem Stroke

Researchers demonstrated that brain-derived neurotrophic factor (BDNF)- and distal-less homeobox 2 (Dlx2)-modified neural stem cells differentiated into GABAergic neurons, integrated into and reconstituted the host neural networks, and alleviated the ischemic injury.