KLF6 Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Autophagy

After ischemia-reperfusion (I/R) injury, scientists found that Krüppel-like factor (KLF) 6 expression in mice and hepatocytes was significantly upregulated. Mice were then subjected to I/R following injection of shKLF6- and KLF6-overexpressing adenovirus through the tail vein.