Newsletters

[Hannover Medical School ] The Joachim Herz Foundation has selected the postdoc Carlos Hernandez Bautista, PhD student in the "Regenerative Sciences" PhD program at Hannover Medical School (MHH) and his project "Development of sustainable biomedicine for heart regeneration" for the "Add-on Fellowship for Interdisciplinary Life Science" and is supporting him with a grant of 15,000 euros.

[March of Dimes] March of Dimes announced leading hematologist and stem cell scientist Dr. Leonard Zon as the winner of the 2026 March of Dimes Richard B Johnston Jr, MD Prize for his work in developmental biology.

[Journal of the American Chemical Society] Researchers introduced a gelatin-based coacervate matrix with phase-transition-mediated tunable mechanics to recapitulate the biophysical cues of pre- and peri-implantation stages.

[Genes & Development] Scientists compared the dynamics of cytoplasmic versus chromatin-bound transcriptomes of naive and primed hESCs as well as fibroblasts. They found a remarkable enrichment for RNA transcribed from α-satellite repeat in the chromatin fraction of naive hESCs compared with primed hESCs.

[Biomaterials Science] Human fetal cardiomyocytes were isolated and their natural geometrical micro/nanotopography was imprinted on polydimethylsiloxane (PDMS) surfaces with different stiffnesses combined with tailored biochemical factors, and the impact of the three factors on the differentiation of hiPSC-derived CM was evaluated.

[Stem Cells] Investigators developed a fast and efficient strategy to generate sclerotomal progenitors by accelerated induction from primitive streak through modulating BMP and SHH signaling, achieving an 86.9% differentiation efficiency.

[Scientific Reports] Researchers aimed to reveal the zinc dynamics in the pluripotent PSCs and during pancreatic differentiation. Using a ⁶⁷Zn-stable isotope-replaced medium, they measured zinc uptake into cells in undifferentiated iPSCs and during pancreatic differentiation.

[BMC Bioinformatics] Scientists developed ColonyQuant, an open-source platform that integrates automated colony segmentation, alkaline phosphatase intensity quantification, morphometric profiling, and statistical classification into a single workflow.

[International Journal of Stem Cells] The authors identified STOML2 as a key pluripotency regulator and provides new insight into intrinsic stem cell fate control. To identify novel regulators of hPSC proliferation, transcriptomic profiling of undifferentiated hPSCs and somatic cells was performed via next-generation sequencing.

[Cellular & Molecular Biology Letters] Scientists discuss current strategies for differentiating hPSCs into mesenchymal stem cells (MSCs) and summarize the key signaling pathways, with a focus on the transcriptional regulators that govern these lineage-specific differentiation routes.

[Regenerative Medicine] The authors explore the potential iPSCs offer in cancer therapy, challenges such as teratoma formation, high production costs, and scalability issues. Futhermore, they investigate the use of iPSC-derived immune cells and regenerative therapies in treating various cancers.

[Verdiva Bio Limited] Verdiva Bio Limited announced the completion of enrollment for its Phase IIb EVOLVE-2 clinical study of VRB-101, a once-weekly oral, cAMP-biased, GLP-1 peptide analog candidate for body weight reduction in people with overweight or obesity.