NewslettersMammary Cell NewsAcquired Secondary HER2 Mutations Enhance HER2/MAPK Signaling and Promote Resistance to HER2 Kinase Inhibition in Breast CancerBy Noshin Noorjahan - July 13, 20230153Investigators showed that secondary acquired HER2T862A and HER2L755S mutations promoted resistance to HER2 tyrosine kinase inhibitors via enhanced HER2 activation and impaired neratinib binding.[Cancer Research]Abstract