Exogenous Hydrogen Sulfide Alleviates Hepatic Endoplasmic Reticulum Stress via SIRT1/FoxO1/PCSK9 Pathway in NAFLD

Investigators studied the influence of exogenous Hydrogen sulfide (H2S) on nonalcoholic fatty liver disease (NAFLD) and its potential mechanism. In vivo, NAFLD model was induced by high-fat diet for 12 weeks, followed by intraperitoneal injection of exogenous H2S intervention for 4 weeks.