Depletion of circ_0088046 Suppressed Cell Growth and Motility of Hepatocellular Carcinoma via circ_0088046-miR-1299-RTKN2 ceRNA Pathway

Researchers explored the role and mechanism of circ_0088046 in HCC progression. Quantitative real-time polymerase chain reaction, western blot and immunohistochemistry assays were used to detect the mRNA and protein expression of circ_0088046, miR-1299, Rhotekin 2 (RTKN2), Bax, Bcl-2, E-cadherin and Ki-67.