Tumor Targeting and Therapeutic Assessments of RNA Nanoparticles Carrying α9-nAchR Aptamer and Anti-miR-21 on Triple-Negative Breast Cancers

Scientists utilized thermodynamically stable three-way junction pRNA as the core to construct RNA nanoparticles with α9-nicotinic acetylcholine receptor (nAchR) RNA aptamer as a targeting ligand and an anti-miR21 as a therapeutic module.