Targeted Nanodelivery of siRNA against KRAS G12D Inhibits Pancreatic Cancer

By
Laurisa Dohm
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0
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Investigators reported that cRGD peptide-modified bioresponsive chimaeric polymersomes mediated highly efficient siKRAS delivery to PANC-1 tumor, potently silencing KRAS G12D mRNA in tumor cells and effectively suppressing pancreatic cancer tumor growth in mice.
[Acta Biomaterialia]
Abstract