Umbilical Cord Mesenchymal Stem Cells Overexpressing CXCR7 Facilitate Treatment of ARDS-Associated Pulmonary Fibrosis via Inhibition of Notch/Jag1 Mediated by the Wnt/β-Catenin Pathway

The authors examined whether overexpression of C-X-C chemokine receptor type 7 (CXCR7) in umbilical cord MSCs could improve their homing efficiency, and therefore, improve their effectiveness in fibrosis repair at the site of lung injury caused by acute respiratory distress syndrome.