Placental Expanded Mesenchymal-Like Cells (PLX-R18) for Poor Graft Function after Hematopoietic Cell Transplantation: A Phase I Study

PLX-R18, a placental-derived mesenchymal-like cell product, was expanded ex vivo in a 3D environment. This phase I, first-in-human study included 21 patients with incomplete hematopoietic recovery post-HCT, who were treated with escalating doses of PLX-R18.