hUC-MSC-EV-miR-24 Enhances the Protective Effect of Dexmedetomidine Preconditioning against Myocardial Ischemia–Reperfusion Injury through the KEAP1/Nrf2/HO-1 Signaling

Researchers collected and identified human umbilical cord-MSCs and extracted extracellular vesicles, which were co-cultured with dexmedetomidine-preconditioned hypoxia/reoxygenation cardiomyocyte models or injected into ischemic-reperfusion mouse models.