Identification of a Novel PAK1/HDAC6 Dual Inhibitor ZMF-23 That Triggers Tubulin-Stathmin Regulated Cell Death in Triple Negative Breast Cancer

Researchers discovered a novel dual-targeting PAK1/HDAC6 inhibitor which presented profound inhibitory activity against PAK1 and HDAC6 and robust antiproliferative potency in MDA-MB-231 cells.