Combined FOLFOX4 with All-Trans Retinoic Acid Versus FOLFOX4 with Placebo in Treatment of Advanced Hepatocellular Carcinoma with Extrahepatic Metastasis: A Randomized, Double-Blind Comparative Study

In this randomized, double-blind, placebo-controlled study, investigators assessed the efficacy and safety of FOLFOX4 with all-trans-retinoic acid as a palliative treatment for HCC patients with extrahepatic metastasis, compared to FOLFOX4 with a placebo.